Databases - Revision history

Kirilas: Removed reference to Single Structure View

2018-04-19T07:22:47Z

Removed reference to Single Structure View

← Older revision		Revision as of 07:22, 19 April 2018
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	__NOTOC__		__NOTOC__
	[[File:data_source_databases.png\|left]]		[[File:data_source_databases.png\|left]]
	The '''Databases''' node in the '''Data source''' panel presents a selection of reference databases that were used for the development of predictive models included in '''ACD/Percepta'''. These databases are fully browsable and searchable in the '''[[Spreadsheet View\|Spreadsheet]]''' ~~or '''[[Single Record View]]''' workspaces~~, but they are read-only and cannot be saved or exported.		The '''Databases''' node in the '''Data source''' panel presents a selection of reference databases that were used for the development of predictive models included in '''ACD/Percepta'''. These databases are fully browsable and searchable in the '''[[Spreadsheet View\|Spreadsheet]]''' workspace, but they are read-only and cannot be saved or exported.

	[[Databases#Absolv\|AbSolv DB]]<br>		[[Databases#Absolv\|AbSolv DB]]<br>

Kirilas: /* AbSolv DB */

2016-05-03T09:42:27Z

AbSolv DB

← Older revision		Revision as of 09:42, 3 May 2016
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	==AbSolv DB==		==AbSolv DB==

	A fully searchable Absolv database lists ~~more than 5~~,000 compounds providing their names, CAS registry numbers, literature values of Abraham solvation parameters and references. This data compilation includes training and test sets used in building and evaluating Absolv predictive algorithms. Fields:		A fully searchable Absolv database lists almost 8,000 compounds providing their names, CAS registry numbers, literature values of Abraham solvation parameters and references. This data compilation includes training and test sets used in building and evaluating Absolv predictive algorithms. Fields:
	* Alpha, BetaH, Beta O, LogL16, PiH2, R2 – Literature values of Abraham solvation parameters		* Alpha, BetaH, Beta O, LogL16, PiH2, R2 – Literature values of Abraham solvation parameters
	* CAS – Chemical Abstracts Service registry number (if available)</span>		* CAS – Chemical Abstracts Service registry number (if available)</span>
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	<span id="Absorption">		<span id="Absorption">

	==Absorption DB==		==Absorption DB==

Kristina at 15:23, 12 February 2013

2013-02-12T15:23:10Z

← Older revision		Revision as of 15:23, 12 February 2013
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	A fully searchable Absolv database lists more than 5,000 compounds providing their names, CAS registry numbers, literature values of Abraham solvation parameters and references. This data compilation includes training and test sets used in building and evaluating Absolv predictive algorithms. Fields:		A fully searchable Absolv database lists more than 5,000 compounds providing their names, CAS registry numbers, literature values of Abraham solvation parameters and references. This data compilation includes training and test sets used in building and evaluating Absolv predictive algorithms. Fields:
	*Alpha, BetaH, Beta O, LogL16, PiH2, R2 – Literature values of Abraham solvation parameters		* Alpha, BetaH, Beta O, LogL16, PiH2, R2 – Literature values of Abraham solvation parameters
	*CAS – Chemical Abstracts Service registry number (if available)</span>		* CAS – Chemical Abstracts Service registry number (if available)</span>

Kristina at 15:22, 12 February 2013

2013-02-12T15:22:04Z

← Older revision		Revision as of 15:22, 12 February 2013
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	[[Databases#Absorption\|Absorption DB]]<br>		[[Databases#Absorption\|Absorption DB]]<br>
	[[Databases#Bioavailability\|Bioavailability DB]]<br>		[[Databases#Bioavailability\|Bioavailability DB]]<br>
	[[Databases#~~LogP~~\|LogP DB]]<br>		[[Databases#Logp\|LogP DB]]<br>
	[[Databases#Mutagenicity\|Mutagenicity DB]]<br>		[[Databases#Mutagenicity\|Mutagenicity DB]]<br>
	[[Databases#pgp\|P-gp DB]]<br>		[[Databases#pgp\|P-gp DB]]<br>
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	<span id="Absolv">		<span id="Absolv">
	==~~Absolv~~ DB==		==AbSolv DB==

	A fully searchable Absolv database lists more than 5,000 compounds providing their names, CAS registry numbers, literature values of Abraham solvation parameters and references. This data compilation includes training and test sets used in building and evaluating Absolv predictive algorithms. Fields:		A fully searchable Absolv database lists more than 5,000 compounds providing their names, CAS registry numbers, literature values of Abraham solvation parameters and references. This data compilation includes training and test sets used in building and evaluating Absolv predictive algorithms. Fields:
	*Alpha, BetaH, Beta O, LogL16, PiH2, R2 – Literature values of Abraham solvation parameters		*Alpha, BetaH, Beta O, LogL16, PiH2, R2 – Literature values of Abraham solvation parameters
	*CAS – Chemical Abstracts Service registry number (if available)</span>		*CAS – Chemical Abstracts Service registry number (if available)</span>


	<span id="Absorption">		<span id="Absorption">
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	** Poor – <30%		** Poor – <30%
	* Comment – provides comments regarding the extent of absorption from the original literature.</span>		* Comment – provides comments regarding the extent of absorption from the original literature.</span>


	<span id="Bioavailability">		<span id="Bioavailability">
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	*%F (oral) – averaged experimental oral bioavailability (human data) value		*%F (oral) – averaged experimental oral bioavailability (human data) value
	*%F (oral) lower and upper limit – interval of bioavailability reported in clinical trials and review articles</span>		*%F (oral) lower and upper limit – interval of bioavailability reported in clinical trials and review articles</span>


	<span id="Logp">		<span id="Logp">
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	A fully searchable LogP database contains 18,412 compounds with experimental LogP values along with references and comments.</span>		A fully searchable LogP database contains 18,412 compounds with experimental LogP values along with references and comments.</span>


	<span id="Mutagenicity">		<span id="Mutagenicity">
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	** SA – spiral assay		** SA – spiral assay
	* References – complete references for the corresponding experiment </span>		* References – complete references for the corresponding experiment </span>


	<span id="pgp">		<span id="pgp">
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	** MDR reversion – sensitization of P-gp expressing cells to “MDR profile” drugs (taxanes, anthracyclines, vinca alkaloids)		** MDR reversion – sensitization of P-gp expressing cells to “MDR profile” drugs (taxanes, anthracyclines, vinca alkaloids)
	** P-gp ATPase modulation – activation or inhibition of P-gp ATPase. This assay does not differentiate P-gp substrates and inhibitors.</span>		** P-gp ATPase modulation – activation or inhibition of P-gp ATPase. This assay does not differentiate P-gp substrates and inhibitors.</span>



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	<span id="~~solubility~~">
			<span id="Solubility">
	==Solubility DB==		==Solubility DB==

Kristina at 14:53, 12 February 2013

2013-02-12T14:53:36Z

← Older revision		Revision as of 14:53, 12 February 2013
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	The '''Databases''' node in the '''Data source''' panel presents a selection of reference databases that were used for the development of predictive models included in '''ACD/Percepta'''. These databases are fully browsable and searchable in the '''[[Spreadsheet View\|Spreadsheet]]''' or '''[[Single Record View]]''' workspaces, but they are read-only and cannot be saved or exported.		The '''Databases''' node in the '''Data source''' panel presents a selection of reference databases that were used for the development of predictive models included in '''ACD/Percepta'''. These databases are fully browsable and searchable in the '''[[Spreadsheet View\|Spreadsheet]]''' or '''[[Single Record View]]''' workspaces, but they are read-only and cannot be saved or exported.

	[[Databases#Absolv\|AbSolv DB]]		[[Databases#Absolv\|AbSolv DB]]<br>
	[[Databases#Absorption\|Absorption DB]]		[[Databases#Absorption\|Absorption DB]]<br>
	[[Databases#Bioavailability\|Bioavailability DB]]		[[Databases#Bioavailability\|Bioavailability DB]]<br>
	[[Databases#LogP\|LogP DB]]		[[Databases#LogP\|LogP DB]]<br>
	[[Databases#Mutagenicity\|Mutagenicity DB]]		[[Databases#Mutagenicity\|Mutagenicity DB]]<br>
	[[Databases#pgp\|P-gp DB]]		[[Databases#pgp\|P-gp DB]]<br>
	[[Databases#pka\|pKa DB]]		[[Databases#pka\|pKa DB]]<br>
	[[Databases#Solubility\|Solubility DB]]		[[Databases#Solubility\|Solubility DB]]<br>

Kristina at 14:52, 12 February 2013

2013-02-12T14:52:43Z

← Older revision		Revision as of 14:52, 12 February 2013
Line 1:		Line 1:
			__NOTOC__
	[[File:data_source_databases.png\|left]]		[[File:data_source_databases.png\|left]]
	The '''Databases''' node in the '''Data source''' panel presents a selection of reference databases that were used for the development of predictive models included in '''ACD/Percepta'''. These databases are fully browsable and searchable in the '''[[Spreadsheet View\|Spreadsheet]]''' or '''[[Single Record View]]''' workspaces, but they are read-only and cannot be saved or exported.		The '''Databases''' node in the '''Data source''' panel presents a selection of reference databases that were used for the development of predictive models included in '''ACD/Percepta'''. These databases are fully browsable and searchable in the '''[[Spreadsheet View\|Spreadsheet]]''' or '''[[Single Record View]]''' workspaces, but they are read-only and cannot be saved or exported.

			[[Databases#Absolv\|AbSolv DB]]
			[[Databases#Absorption\|Absorption DB]]
			[[Databases#Bioavailability\|Bioavailability DB]]
			[[Databases#LogP\|LogP DB]]
			[[Databases#Mutagenicity\|Mutagenicity DB]]
			[[Databases#pgp\|P-gp DB]]
			[[Databases#pka\|pKa DB]]
			[[Databases#Solubility\|Solubility DB]]


			<span id="Absolv">


	==Absolv DB==		==Absolv DB==

	A fully searchable Absolv database lists more than 5,000 compounds providing their names, CAS registry numbers, literature values of Abraham solvation parameters and references. This data compilation includes training and test sets used in building and evaluating Absolv predictive algorithms. Fields:		A fully searchable Absolv database lists more than 5,000 compounds providing their names, CAS registry numbers, literature values of Abraham solvation parameters and references. This data compilation includes training and test sets used in building and evaluating Absolv predictive algorithms. Fields:
	*Alpha, BetaH, Beta O, LogL16, PiH2, R2 – Literature values of Abraham solvation parameters		*Alpha, BetaH, Beta O, LogL16, PiH2, R2 – Literature values of Abraham solvation parameters
	*CAS – Chemical Abstracts Service registry number (if available)		*CAS – Chemical Abstracts Service registry number (if available)</span>


			<span id="Absorption">
	==Absorption DB==		==Absorption DB==

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	** Moderate – 30%-70%		** Moderate – 30%-70%
	** Poor – <30%		** Poor – <30%
	* Comment – provides comments regarding the extent of absorption from the original literature.		* Comment – provides comments regarding the extent of absorption from the original literature.</span>


			<span id="Bioavailability">
	==Bioavailability DB==		==Bioavailability DB==

	A fully searchable Bioavailability database contains 790 compounds with experimental %F (oral) values. Fields:		A fully searchable Bioavailability database contains 790 compounds with experimental %F (oral) values. Fields:
	*%F (oral) – averaged experimental oral bioavailability (human data) value		*%F (oral) – averaged experimental oral bioavailability (human data) value
	*%F (oral) lower and upper limit – interval of bioavailability reported in clinical trials and review articles		*%F (oral) lower and upper limit – interval of bioavailability reported in clinical trials and review articles</span>


			<span id="Logp">
	==LogP DB==		==LogP DB==

	A fully searchable LogP database contains 18,412 compounds with experimental LogP values along with references and comments.		A fully searchable LogP database contains 18,412 compounds with experimental LogP values along with references and comments.</span>


			<span id="Mutagenicity">
	==Mutagenicity DB==		==Mutagenicity DB==

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	** FL – fluctation test		** FL – fluctation test
	** SA – spiral assay		** SA – spiral assay
	* References – complete references for the corresponding experiment		* References – complete references for the corresponding experiment </span>


			<span id="pgp">
	==P-gp DB==		==P-gp DB==

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	** Drug efflux inhibition – inhibition of drug efflux in P-gp expressing cells.		** Drug efflux inhibition – inhibition of drug efflux in P-gp expressing cells.
	** MDR reversion – sensitization of P-gp expressing cells to “MDR profile” drugs (taxanes, anthracyclines, vinca alkaloids)		** MDR reversion – sensitization of P-gp expressing cells to “MDR profile” drugs (taxanes, anthracyclines, vinca alkaloids)
	** P-gp ATPase modulation – activation or inhibition of P-gp ATPase. This assay does not differentiate P-gp substrates and inhibitors.		** P-gp ATPase modulation – activation or inhibition of P-gp ATPase. This assay does not differentiate P-gp substrates and inhibitors.</span>


			<span id="pka">
			==pKa DB==

			A fully searchable pKa database contains 15,924 compounds with values of the acidic dissociation constants measured at various experimental conditions along with the literature references. <br>Fields:
			* Name - the compound's name in the database
			* Ionic form - presented in the form "HxL", where x is the number of dissociable protons in the drawn structure
			* pKa - the list of experimental pKa values for a compound
			* Error - the estimated error of experimental determination, if available
			* Temperature - in degrees Celsius
			* Ionic Strength - in moles per liter
			* Equilibrium - indicates the dissociation stage described by the given pKa value
			* Reference - literature citation </span>


			<span id="solubility">
	==Solubility DB==		==Solubility DB==

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	* Sw – experimental solubility values are given in Sw (mg/ml) units		* Sw – experimental solubility values are given in Sw (mg/ml) units
	<br>		<br>
	'''Note:''' Qualitative assessment and experimental solubility come as independent data often from the different references. Therefore not all of the compounds from the database have both of these fields available.		'''Note:''' Qualitative assessment and experimental solubility come as independent data often from the different references. Therefore not all of the compounds from the database have both of these fields available.</span>


	~~==pKa DB==~~

	~~A fully searchable pKa database contains 15,924 compounds with values of the acidic dissociation constants measured at various experimental conditions along with the literature references~~. <br>~~Fields:~~
	* Name - the compound's name in the database
	* Ionic form - presented in the form "HxL", where x is the number of dissociable protons in the drawn structure
	* pKa - the list of experimental pKa values for a compound
	* Error - the estimated error of experimental determination, if available
	* Temperature - in degrees Celsius
	* Ionic Strength - in moles per liter
	* Equilibrium - indicates the dissociation stage described by the given pKa value
	* Reference - literature citation

Kristina at 14:45, 12 February 2013

2013-02-12T14:45:45Z

← Older revision		Revision as of 14:45, 12 February 2013
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			[[File:data_source_databases.png\|left]]
	The '''Databases''' node in the '''Data source''' panel presents a selection of reference databases that were used for the development of predictive models included in '''ACD/Percepta'''. These databases are fully browsable and searchable in the '''[[Spreadsheet View\|Spreadsheet]]''' or '''[[Single Record View]]''' workspaces, but they are read-only and cannot be saved or exported.		The '''Databases''' node in the '''Data source''' panel presents a selection of reference databases that were used for the development of predictive models included in '''ACD/Percepta'''. These databases are fully browsable and searchable in the '''[[Spreadsheet View\|Spreadsheet]]''' or '''[[Single Record View]]''' workspaces, but they are read-only and cannot be saved or exported.






	==Absolv DB==		==Absolv DB==
	~~<br>[[File:data_source_databases.png\|left]]<br>~~

	A fully searchable Absolv database lists more than 5,000 compounds providing their names, CAS registry numbers, literature values of Abraham solvation parameters and references. This data compilation includes training and test sets used in building and evaluating Absolv predictive algorithms. Fields:		A fully searchable Absolv database lists more than 5,000 compounds providing their names, CAS registry numbers, literature values of Abraham solvation parameters and references. This data compilation includes training and test sets used in building and evaluating Absolv predictive algorithms. Fields:
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	==Absorption DB==		==Absorption DB==


	A fully searchable Absorption database contains 865 compounds with experimental human intestinal passive absorption values. Fields:		A fully searchable Absorption database contains 865 compounds with experimental human intestinal passive absorption values. Fields:
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	==Bioavailability DB==		==Bioavailability DB==


	A fully searchable Bioavailability database contains 790 compounds with experimental %F (oral) values. Fields:		A fully searchable Bioavailability database contains 790 compounds with experimental %F (oral) values. Fields:
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	==LogP DB==		==LogP DB==


	A fully searchable LogP database contains 18,412 compounds with experimental LogP values along with references and comments.		A fully searchable LogP database contains 18,412 compounds with experimental LogP values along with references and comments.
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	==Mutagenicity DB==		==Mutagenicity DB==


	A fully searchable Mutagenicity database contains 5511 compounds. Fields:		A fully searchable Mutagenicity database contains 5511 compounds. Fields:
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	==P-gp DB==		==P-gp DB==


	A fully searchable Pgp database contains 2,290 compounds with experimental values. Fields:		A fully searchable Pgp database contains 2,290 compounds with experimental values. Fields:
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	==Solubility DB==		==Solubility DB==


	A fully searchable Solubility database contains 5,435 compounds along with their chemical names, literature references and experimental data that is expressed in both qualitative and quantitative manner. This compilation is a part of the training set used in building the algorithm for prediction of aqueous solubility in pure water. Fields:		A fully searchable Solubility database contains 5,435 compounds along with their chemical names, literature references and experimental data that is expressed in both qualitative and quantitative manner. This compilation is a part of the training set used in building the algorithm for prediction of aqueous solubility in pure water. Fields:
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	==pKa DB==		==pKa DB==


	A fully searchable pKa database contains 15,924 compounds with values of the acidic dissociation constants measured at various experimental conditions along with the literature references. <br>Fields:		A fully searchable pKa database contains 15,924 compounds with values of the acidic dissociation constants measured at various experimental conditions along with the literature references. <br>Fields:

Kristina at 14:27, 12 February 2013

2013-02-12T14:27:22Z

← Older revision		Revision as of 14:27, 12 February 2013
Line 2:		Line 2:


			==Absolv DB==
	<br>[[File:data_source_databases.png\|left]]<br>		<br>[[File:data_source_databases.png\|left]]<br>
	~~==Absolv DB==~~


	A fully searchable Absolv database lists more than 5,000 compounds providing their names, CAS registry numbers, literature values of Abraham solvation parameters and references. This data compilation includes training and test sets used in building and evaluating Absolv predictive algorithms. Fields:		A fully searchable Absolv database lists more than 5,000 compounds providing their names, CAS registry numbers, literature values of Abraham solvation parameters and references. This data compilation includes training and test sets used in building and evaluating Absolv predictive algorithms. Fields:
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	==pKa DB ~~(reikia pildyti)~~==		==pKa DB==

Kristina: Created page with "The '''Databases''' node in the '''Data source''' panel presents a selection of reference databases that were used for the development of predictive models included in '''ACD/..."

2013-02-12T14:26:07Z

Created page with "The '''Databases''' node in the '''Data source''' panel presents a selection of reference databases that were used for the development of predictive models included in '''ACD/..."

New page

The '''Databases''' node in the '''Data source''' panel presents a selection of reference databases that were used for the development of predictive models included in '''ACD/Percepta'''. These databases are fully browsable and searchable in the '''[[Spreadsheet View|Spreadsheet]]''' or '''[[Single Record View]]''' workspaces, but they are read-only and cannot be saved or exported.

<br>[[File:data_source_databases.png|left]]<br>
==Absolv DB==

A fully searchable Absolv database lists more than 5,000 compounds providing their names, CAS registry numbers, literature values of Abraham solvation parameters and references. This data compilation includes training and test sets used in building and evaluating Absolv predictive algorithms. Fields:
*Alpha, BetaH, Beta O, LogL16, PiH2, R2 – Literature values of Abraham solvation parameters
*CAS – Chemical Abstracts Service registry number (if available)

==Absorption DB==

A fully searchable Absorption database contains 865 compounds with experimental human intestinal passive absorption values. Fields:
* Absorption – passive absorption classification:
** Good – >70%
** Moderate – 30%-70%
** Poor – <30%
* Comment – provides comments regarding the extent of absorption from the original literature.

==Bioavailability DB==

A fully searchable Bioavailability database contains 790 compounds with experimental %F (oral) values. Fields:
*%F (oral) – averaged experimental oral bioavailability (human data) value
*%F (oral) lower and upper limit – interval of bioavailability reported in clinical trials and review articles

==LogP DB==

A fully searchable LogP database contains 18,412 compounds with experimental LogP values along with references and comments.

==Mutagenicity DB==

A fully searchable Mutagenicity database contains 5511 compounds. Fields:
*Name – compound’s name in database
* CAS – Chemical Abstracts Service registry number
* Result – displays owerall result:
** + positive
** - negative
** (+) weakly positive
** ? inconclusive, discrepant data
* Groups of fields for the bacteria strains: TA97, TA98, TA100, TA102, TA104, TA1535, TA1537, TA1538, E.Coli.
* With – result for experiment with metabolic activation
* Without – result for experiment without metabolicactivation
* Dose/Solvent:
** dose range
** solvent used
* Activation – metabolic activation system used in the experiment:
** animal source of S9 fraction
** tissue issued
** inducer
* Method – method of experiment:
** PL – plate incorporation
** PR – preincubation,
** SP – spot test
** SU – suspension
** DE – desiccator
** FL – fluctation test
** SA – spiral assay
* References – complete references for the corresponding experiment

==P-gp DB==

A fully searchable Pgp database contains 2,290 compounds with experimental values. Fields:
* Substrate – classification of compounds based on P-gp substrate specificity:
** Yes – P-gp substrate.
** No – P-gp non-substrate.
** Yes/No – possible P-gp substrate. Contradicitive or inconclusive data.
** No/Yes – probably P-gp non-substrate. Contradictive or inconclusive data.
* Efficiency – estimation the effectivity of drug transport by P-gp. “High efficiency” describes compounds that are transported with the rate similar to the best substrates (vinblastine, daunorubicin, paclitaxel).
* Inhibitor – classification of compounds based on P-gp inhibition specificity.
* Potency – estimation the effectivity of P-gp inhibition. “High potency” describes compounds that inhibit P-gp as good as standard inhibitor verapamil or even better.
* In the Assays section, the methods that were used in the analysis of P-gp substrate/inhibitor specificity are listed:
** Substrate (in vitro transport assay) – polarized transport of drugs across P-gp expressing cell monolayers or decreased drug accumulation in MDR cells
** Substrate (in vivo BBB models) – increased distribution of drugs to the brain in P-gp deficient (mdr1a/b(-/-)) mice
** P-gp mediated resistance – P-gp overexpressing (MDR) cells demonstrate resistance to the drug
** Drug efflux inhibition – inhibition of drug efflux in P-gp expressing cells.
** MDR reversion – sensitization of P-gp expressing cells to “MDR profile” drugs (taxanes, anthracyclines, vinca alkaloids)
** P-gp ATPase modulation – activation or inhibition of P-gp ATPase. This assay does not differentiate P-gp substrates and inhibitors.

==Solubility DB==

A fully searchable Solubility database contains 5,435 compounds along with their chemical names, literature references and experimental data that is expressed in both qualitative and quantitative manner. This compilation is a part of the training set used in building the algorithm for prediction of aqueous solubility in pure water. Fields:
* Qualitative – qualitative assessment of compounds solubility in pure water:
** Highly insoluble – Sw < 0.1 mg/ml
** Insoluble – Sw < 1 mg/ml
** Slightly soluble – Sw > 1 mg/ml
** Soluble – Sw > 10 mg/ml
* logSw – experimental solubility values are given in LogSw (mmol/ml) units
* Sw – experimental solubility values are given in Sw (mg/ml) units
<br>
'''Note:''' Qualitative assessment and experimental solubility come as independent data often from the different references. Therefore not all of the compounds from the database have both of these fields available.

==pKa DB (reikia pildyti)==

A fully searchable pKa database contains 15,924 compounds with values of the acidic dissociation constants measured at various experimental conditions along with the literature references. <br>Fields:
* Name - the compound's name in the database
* Ionic form - presented in the form "HxL", where x is the number of dissociable protons in the drawn structure
* pKa - the list of experimental pKa values for a compound
* Error - the estimated error of experimental determination, if available
* Temperature - in degrees Celsius
* Ionic Strength - in moles per liter
* Equilibrium - indicates the dissociation stage described by the given pKa value
* Reference - literature citation

← Older revision		Revision as of 14:53, 12 February 2013
Line 3:		Line 3:
	The '''Databases''' node in the '''Data source''' panel presents a selection of reference databases that were used for the development of predictive models included in '''ACD/Percepta'''. These databases are fully browsable and searchable in the '''[[Spreadsheet View\|Spreadsheet]]''' or '''[[Single Record View]]''' workspaces, but they are read-only and cannot be saved or exported.		The '''Databases''' node in the '''Data source''' panel presents a selection of reference databases that were used for the development of predictive models included in '''ACD/Percepta'''. These databases are fully browsable and searchable in the '''[[Spreadsheet View\|Spreadsheet]]''' or '''[[Single Record View]]''' workspaces, but they are read-only and cannot be saved or exported.

	[[Databases#Absolv\|AbSolv DB]]		[[Databases#Absolv\|AbSolv DB]]<br>
	[[Databases#Absorption\|Absorption DB]]		[[Databases#Absorption\|Absorption DB]]<br>
	[[Databases#Bioavailability\|Bioavailability DB]]		[[Databases#Bioavailability\|Bioavailability DB]]<br>
	[[Databases#LogP\|LogP DB]]		[[Databases#LogP\|LogP DB]]<br>
	[[Databases#Mutagenicity\|Mutagenicity DB]]		[[Databases#Mutagenicity\|Mutagenicity DB]]<br>
	[[Databases#pgp\|P-gp DB]]		[[Databases#pgp\|P-gp DB]]<br>
	[[Databases#pka\|pKa DB]]		[[Databases#pka\|pKa DB]]<br>
	[[Databases#Solubility\|Solubility DB]]		[[Databases#Solubility\|Solubility DB]]<br>